Shar Pei dogs typically enter their senior years around seven to eight years of age, or six and a half years with health issues.

Familial Shar Pei Fever and amyloidosis cause fatal kidney damage by accumulating abnormal protein deposits in vital organs.

Shar Pei dogs with immunoglobulin A deficiency face recurrent ear infections and skin issues from a genetic predisposition.

Hypothyroidism in Shar Pei dogs causes low T3 and T4 hormone levels, reducing energy and metabolism through an autoimmune disease.

Cutaneous mucinosis in Shar Pei involves hyaluronic acid overproduction from the HAS2 gene, creating gelatinous bumps under the skin.

Shar Pei food allergies and intolerances cause scratching and ear infections, requiring diagnosis to manage immune responses.

Shar Pei dogs have a genetic predisposition to demodectic mange because weak immune systems allow Demodex mites to overgrow.

Skin fold dermatitis causes painful infections in Shar Pei wrinkles, but owners can manage the condition to prevent yeast and bacteria overgrowth.

Chronic inflammation and recurring ear infections cause scar tissue buildup that leads to permanent closure of a Shar Pei ear canal.

Shar Pei ear infections occur frequently because narrow ear canals and deep-set ears trap moisture, bacteria, and yeast.